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1:

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis.

Srivastava M, Steinwede K, Kiviranta R, Morko J, Hoymann HG, Länger F, Buhling F, Welte T, Maus UA.

Respir Res. 2008 Jul 18;9:54.

PMID: 18638383 [PubMed - indexed for MEDLINE]

2:

Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis.

Strandjord TP, Madtes DK, Weiss DJ, Sage EH.

Am J Physiol. 1999 Sep;277(3 Pt 1):L628-35.

PMID: 10484471 [PubMed - indexed for MEDLINE]

3:

E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.

Horikawa M, Fujimoto M, Hasegawa M, Matsushita T, Hamaguchi Y, Kawasuji A, Matsushita Y, Fujita T, Ogawa F, Takehara K, Steeber DA, Sato S.

Am J Pathol. 2006 Sep;169(3):740-9.

PMID: 16936251 [PubMed - indexed for MEDLINE]

4:

Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin.

Cabrera S, Gaxiola M, Arreola JL, Ramírez R, Jara P, D'Armiento J, Richards T, Selman M, Pardo A.

Int J Biochem Cell Biol. 2007;39(12):2324-38. Epub 2007 Jul 12.

PMID: 17702637 [PubMed - indexed for MEDLINE]

5:

Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

Hoyles RK, Khan K, Shiwen X, Howat SL, Lindahl GE, Leoni P, du Bois RM, Wells AU, Black CM, Abraham DJ, Denton CP.

Arthritis Rheum. 2008 Apr;58(4):1175-88.

PMID: 18383385 [PubMed - indexed for MEDLINE]

6:

Cathepsins in bleomycin-induced lung injury in rat.

Koslowski R, Knoch K, Kuhlisch E, Seidel D, Kasper M.

Eur Respir J. 2003 Sep;22(3):427-35.

PMID: 14516131 [PubMed - indexed for MEDLINE]

7:

Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47.

Razzaque MS, Hossain MA, Kohno S, Taguchi T.

Virchows Arch. 1998 May;432(5):455-60.

PMID: 9645446 [PubMed - indexed for MEDLINE]

8:

Treatment of bleomycin-induced pulmonary fibrosis by transfer of urokinase-type plasminogen activator genes.

Sisson TH, Hattori N, Xu Y, Simon RH.

Hum Gene Ther. 1999 Sep 20;10(14):2315-23.

PMID: 10515451 [PubMed - indexed for MEDLINE]

9:

Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene.

Tran PL, Weinbach J, Opolon P, Linares-Cruz G, Reynes JP, Grégoire A, Kremer E, Durand H, Perricaudet M.

J Clin Invest. 1997 Feb 15;99(4):608-17.

PMID: 9045862 [PubMed - indexed for MEDLINE]

10:

Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.

Young LR, Pasula R, Gulleman PM, Deutsch GH, McCormack FX.

Am J Respir Cell Mol Biol. 2007 Jul;37(1):67-74. Epub 2007 Mar 15.

PMID: 17363777 [PubMed - indexed for MEDLINE]

11:

Pivotal role of cathepsin K in lung fibrosis.

Bühling F, Röcken C, Brasch F, Hartig R, Yasuda Y, Saftig P, Brömme D, Welte T.

Am J Pathol. 2004 Jun;164(6):2203-16.

PMID: 15161653 [PubMed - indexed for MEDLINE]

12:

Attenuation of bleomycin-induced lung fibrosis by oxymatrine is associated with regulation of fibroblast proliferation and collagen production in primary culture.

Chen X, Sun R, Hu J, Mo Z, Yang Z, Liao D, Zhong N.

Basic Clin Pharmacol Toxicol. 2008 Sep;103(3):278-86. Epub 2008 Jul 18.

PMID: 18684219 [PubMed - indexed for MEDLINE]

13:

The development of bleomycin-induced pulmonary fibrosis in mice deficient for components of the fibrinolytic system.

Swaisgood CM, French EL, Noga C, Simon RH, Ploplis VA.

Am J Pathol. 2000 Jul;157(1):177-87.

PMID: 10880388 [PubMed - indexed for MEDLINE]

14:

Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis.

Fujimoto H, Gabazza EC, Taguchi O, Nishii Y, Nakahara H, Bruno NE, D'Alessandro-Gabazza CN, Kasper M, Yano Y, Nagashima M, Morser J, Broze GJ, Suzuki K, Adachi Y.

Am J Pathol. 2006 Apr;168(4):1086-96.

PMID: 16565485 [PubMed - indexed for MEDLINE]

15:

EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-beta signaling in lung fibroblasts.

Li YJ, Azuma A, Usuki J, Abe S, Matsuda K, Sunazuka T, Shimizu T, Hirata Y, Inagaki H, Kawada T, Takahashi S, Kudoh S, Omura S.

Respir Res. 2006 Jan 27;7:16.

PMID: 16438734 [PubMed - indexed for MEDLINE]

16:

Expression of FACIT collagens XII and XIV during bleomycin-induced pulmonary fibrosis in mice.

Tzortzaki EG, Tischfield JA, Sahota A, Siafakas NM, Gordon MK, Gerecke DR.

Anat Rec A Discov Mol Cell Evol Biol. 2003 Dec;275(2):1073-80.

PMID: 14613307 [PubMed - indexed for MEDLINE]

17:

In situ hybridization analysis of rat lung alpha 1(I) and alpha 2(I) collagen gene expression in pulmonary fibrosis induced by endotracheal bleomycin injection.

Zhang K, Gharaee-Kermani M, McGarry B, Phan SH.

Lab Invest. 1994 Feb;70(2):192-202.

PMID: 7511187 [PubMed - indexed for MEDLINE]

18:

Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis.

Keane MP, Belperio JA, Moore TA, Moore BB, Arenberg DA, Smith RE, Burdick MD, Kunkel SL, Strieter RM.

J Immunol. 1999 May 1;162(9):5511-8.

PMID: 10228032 [PubMed - indexed for MEDLINE]

19:

The role of the receptor for advanced glycation end-products in lung fibrosis.

He M, Kubo H, Ishizawa K, Hegab AE, Yamamoto Y, Yamamoto H, Yamaya M.

Am J Physiol Lung Cell Mol Physiol. 2007 Dec;293(6):L1427-36. Epub 2007 Oct 19.

PMID: 17951314 [PubMed - indexed for MEDLINE]

20:

Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis.

Kimura T, Ishii Y, Yoh K, Morishima Y, Iizuka T, Kiwamoto T, Matsuno Y, Homma S, Nomura A, Sakamoto T, Takahashi S, Sekizawa K.

Am J Pathol. 2006 Jul;169(1):96-104.

PMID: 16816364 [PubMed - indexed for MEDLINE]

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