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1:

Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B.

Xu F, Xu Z, Zhang R, Wu Z, Lim JH, Koga T, Li JD, Shen H.

Respir Res. 2008 Jan 31;9:16.

PMID: 18237405 [PubMed - indexed for MEDLINE]

2:

Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells.

Shuto T, Xu H, Wang B, Han J, Kai H, Gu XX, Murphy TF, Lim DJ, Li JD.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8774-9. Epub 2001 Jul 3.

PMID: 11438700 [PubMed - indexed for MEDLINE]

4:

Leptospiral membrane proteins stimulate pro-inflammatory chemokines secretion by renal tubule epithelial cells through toll-like receptor 2 and p38 mitogen activated protein kinase.

Hung CC, Chang CT, Tian YC, Wu MS, Yu CC, Pan MJ, Vandewalle A, Yang CW.

Nephrol Dial Transplant. 2006 Apr;21(4):898-910. Epub 2005 Dec 8.

PMID: 16339163 [PubMed - indexed for MEDLINE]

5:

Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase.

Shuto T, Imasato A, Jono H, Sakai A, Xu H, Watanabe T, Rixter DD, Kai H, Andalibi A, Linthicum F, Guan YL, Han J, Cato AC, Lim DJ, Akira S, Li JD.

J Biol Chem. 2002 May 10;277(19):17263-70. Epub 2002 Feb 26.

PMID: 11867630 [PubMed - indexed for MEDLINE]

7:

Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways.

Chen R, Lim JH, Jono H, Gu XX, Kim YS, Basbaum CB, Murphy TF, Li JD.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):1087-94.

PMID: 15485666 [PubMed - indexed for MEDLINE]

8:

Streptococcus pneumoniae induced p38 MAPK- and NF-kappaB-dependent COX-2 expression in human lung epithelium.

N'Guessan PD, Hippenstiel S, Etouem MO, Zahlten J, Beermann W, Lindner D, Opitz B, Witzenrath M, Rosseau S, Suttorp N, Schmeck B.

Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1131-8. Epub 2006 Jan 13.

PMID: 16414978 [PubMed - indexed for MEDLINE]

9:

Toll-like receptor 2 and mitogen- and stress-activated kinase 1 are effectors of Mycobacterium avium-induced cyclooxygenase-2 expression in macrophages.

Pathak SK, Bhattacharyya A, Pathak S, Basak C, Mandal D, Kundu M, Basu J.

J Biol Chem. 2004 Dec 31;279(53):55127-36. Epub 2004 Oct 20.

PMID: 15496409 [PubMed - indexed for MEDLINE]

12:

Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells.

Smith MF Jr, Mitchell A, Li G, Ding S, Fitzmaurice AM, Ryan K, Crowe S, Goldberg JB.

J Biol Chem. 2003 Aug 29;278(35):32552-60. Epub 2003 Jun 13.

PMID: 12807870 [PubMed - indexed for MEDLINE]

13:

Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2.

Imasato A, Desbois-Mouthon C, Han J, Kai H, Cato AC, Akira S, Li JD.

J Biol Chem. 2002 Dec 6;277(49):47444-50. Epub 2002 Sep 27.

PMID: 12356755 [PubMed - indexed for MEDLINE]

14:

Toll-like receptor 2-dependent NF-kappaB activation is involved in nontypeable Haemophilus influenzae-induced monocyte chemotactic protein 1 up-regulation in the spiral ligament fibrocytes of the inner ear.

Moon SK, Woo JI, Lee HY, Park R, Shimada J, Pan H, Gellibolian R, Lim DJ.

Infect Immun. 2007 Jul;75(7):3361-72. Epub 2007 Apr 23.

PMID: 17452470 [PubMed - indexed for MEDLINE]

15:

Lipoteichoic acid-induced nitric oxide synthase expression in RAW 264.7 macrophages is mediated by cyclooxygenase-2, prostaglandin E2, protein kinase A, p38 MAPK, and nuclear factor-kappaB pathways.

Chang YC, Li PC, Chen BC, Chang MS, Wang JL, Chiu WT, Lin CH.

Cell Signal. 2006 Aug;18(8):1235-43. Epub 2005 Nov 11.

PMID: 16289764 [PubMed - indexed for MEDLINE]

16:

Synergistic activation of NF-kappaB by nontypeable Haemophilus influenzae and tumor necrosis factor alpha.

Watanabe T, Jono H, Han J, Lim DJ, Li JD.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3563-8. Epub 2004 Mar 1.

PMID: 14993593 [PubMed - indexed for MEDLINE]

17:

Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells.

Lee HY, Takeshita T, Shimada J, Akopyan A, Woo JI, Pan H, Moon SK, Andalibi A, Park RK, Kang SH, Kang SS, Gellibolian R, Lim DJ.

BMC Infect Dis. 2008 Jun 25;8:87.

PMID: 18578886 [PubMed - indexed for MEDLINE]

19:

Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kappaB activation and COX-2 expression in human breast epithelial cells.

Kim JH, Na HK, Pak YK, Lee YS, Lee SJ, Moon A, Surh YJ.

Chem Biol Interact. 2008 Jan 30;171(2):133-41. Epub 2007 Jul 26.

PMID: 17767925 [PubMed - indexed for MEDLINE]

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