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1:

Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial.

Choudhury AB, Dawson CM, Kilvington HE, Eldridge S, James WY, Wedzicha JA, Feder GS, Griffiths CJ.

Respir Res. 2007 Dec 27;8:93.

PMID: 18162137 [PubMed - indexed for MEDLINE]

2:

Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. International COPD Study Group.

Paggiaro PL, Dahle R, Bakran I, Frith L, Hollingworth K, Efthimiou J.

Lancet. 1998 Mar 14;351(9105):773-80. Erratum in: Lancet 1998 Jun 27;351(9120):1968.

PMID: 9519948 [PubMed - indexed for MEDLINE]

3:

Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial.

Wouters EF, Postma DS, Fokkens B, Hop WC, Prins J, Kuipers AF, Pasma HR, Hensing CA, Creutzberg EC; COSMIC (COPD and Seretide: a Multi-Center Intervention and Characterization) Study Group.

Thorax. 2005 Jun;60(6):480-7.

PMID: 15923248 [PubMed - indexed for MEDLINE]

4:

Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial.

Aaron SD, Vandemheen KL, Fergusson D, Maltais F, Bourbeau J, Goldstein R, Balter M, O'Donnell D, McIvor A, Sharma S, Bishop G, Anthony J, Cowie R, Field S, Hirsch A, Hernandez P, Rivington R, Road J, Hoffstein V, Hodder R, Marciniuk D, McCormack D, Fox G, Cox G, Prins HB, Ford G, Bleskie D, Doucette S, Mayers I, Chapman K, Zamel N, FitzGerald M; Canadian Thoracic Society/Canadian Respiratory Clinical Research Consortium.

Ann Intern Med. 2007 Apr 17;146(8):545-55. Epub 2007 Feb 19. Summary for patients in: Ann Intern Med. 2007 Apr 17;146(8):I12.

PMID: 17310045 [PubMed - indexed for MEDLINE]

5:

Inhaled corticosteroids for stable chronic obstructive pulmonary disease.

Yang IA, Fong KM, Sim EH, Black PN, Lasserson TJ.

Cochrane Database Syst Rev. 2007 Apr 18;(2):CD002991. Review.

PMID: 17443520 [PubMed - indexed for MEDLINE]

6:

Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial.

Calverley P, Pauwels R, Vestbo J, Jones P, Pride N, Gulsvik A, Anderson J, Maden C; TRial of Inhaled STeroids ANd long-acting beta2 agonists study group.

Lancet. 2003 Feb 8;361(9356):449-56. Erratum in: Lancet. 2003 May 10;361(9369):1660.

PMID: 12583942 [PubMed - indexed for MEDLINE]

7:

The impact of inhaled corticosteroid and long-acting beta-agonist combination therapy on outcomes in COPD.

Hanania NA.

Pulm Pharmacol Ther. 2008;21(3):540-50. Epub 2008 Jan 6. Review.

PMID: 18280761 [PubMed - indexed for MEDLINE]

8:

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, Yates JC, Vestbo J; TORCH investigators.

N Engl J Med. 2007 Feb 22;356(8):775-89.

PMID: 17314337 [PubMed - indexed for MEDLINE]

9:

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial.

Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA, Maslen TK.

BMJ. 2000 May 13;320(7245):1297-303.

PMID: 10807619 [PubMed - indexed for MEDLINE]

10:

Efficacy and safety of tiotropium in COPD patients in primary care--the SPiRiva Usual CarE (SPRUCE) study.

Freeman D, Lee A, Price D.

Respir Res. 2007 Jul 2;8:45.

PMID: 17605774 [PubMed - indexed for MEDLINE]

11:

Should inhaled corticosteroids be used in the long term treatment of chronic obstructive pulmonary disease?

Burge S.

Drugs. 2001;61(11):1535-44. Review.

PMID: 11577791 [PubMed - indexed for MEDLINE]

12:

[Inhaled corticosteroids in patients with COPD: maintain current guidelines]

Heijdra YF.

Ned Tijdschr Geneeskd. 2007 Oct 6;151(40):2195-7. Dutch.

PMID: 17969568 [PubMed - indexed for MEDLINE]

13:

The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide.

Wedzicha JA, Calverley PM, Seemungal TA, Hagan G, Ansari Z, Stockley RA; INSPIRE Investigators.

Am J Respir Crit Care Med. 2008 Jan 1;177(1):19-26. Epub 2007 Oct 4.

PMID: 17916806 [PubMed - indexed for MEDLINE]

14:

Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease.

Nannini LJ, Cates CJ, Lasserson TJ, Poole P.

Cochrane Database Syst Rev. 2007 Oct 17;(4):CD006826. Review.

PMID: 17943917 [PubMed - indexed for MEDLINE]

15:

The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: a double-blind, placebo-controlled biopsy study.

Hattotuwa KL, Gizycki MJ, Ansari TW, Jeffery PK, Barnes NC.

Am J Respir Crit Care Med. 2002 Jun 15;165(12):1592-6.

PMID: 12070058 [PubMed - indexed for MEDLINE]

16:

A 1-year prospective cost-effectiveness analysis of roflumilast for the treatment of patients with severe chronic obstructive pulmonary disease.

Rutten-van Mölken MP, van Nooten FE, Lindemann M, Caeser M, Calverley PM.

Pharmacoeconomics. 2007;25(8):695-711.

PMID: 17640111 [PubMed - indexed for MEDLINE]

17:

Inhaled corticosteroids and the risk of a first exacerbation in COPD patients.

de Melo MN, Ernst P, Suissa S.

Eur Respir J. 2004 May;23(5):692-7.

PMID: 15176681 [PubMed - indexed for MEDLINE]

19:

Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive pulmonary disease: the COPE study.

van der Valk P, Monninkhof E, van der Palen J, Zielhuis G, van Herwaarden C.

Am J Respir Crit Care Med. 2002 Nov 15;166(10):1358-63. Epub 2002 Sep 5.

PMID: 12406823 [PubMed - indexed for MEDLINE]

20:

Combined salmeterol/fluticasone propionate versus fluticasone propionate alone in mild asthma : a placebo-controlled comparison.

Boonsawat W, Goryachkina L, Jacques L, Frith L.

Clin Drug Investig. 2008;28(2):101-11.

PMID: 18211118 [PubMed - indexed for MEDLINE]

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