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2:

In Vitro metabolism of ciclesonide in human lung and liver precision-cut tissue slices.

Nave R, Fisher R, Zech K.

Biopharm Drug Dispos. 2006 May;27(4):197-207.

PMID: 16566061 [PubMed - indexed for MEDLINE]

4:

Ciclesonide uptake and metabolism in human alveolar type II epithelial cells (A549).

Nonaka T, Nave R, McCracken N, Kawashimo A, Katsuura Y.

BMC Pharmacol. 2007 Sep 27;7:12.

PMID: 17900334 [PubMed - indexed for MEDLINE]

5:

Comparison of the oropharyngeal deposition of inhaled ciclesonide and fluticasone propionate in patients with asthma.

Richter K, Kanniess F, Biberger C, Nave R, Magnussen H.

J Clin Pharmacol. 2005 Feb;45(2):146-52.

PMID: 15647406 [PubMed - indexed for MEDLINE]

6:

In vitro metabolism of ciclesonide in human nasal epithelial cells.

Sato H, Nave R, Nonaka T, Mochizuki T, Takahama S, Kondo S.

Biopharm Drug Dispos. 2007 Jan;28(1):43-50.

PMID: 17117454 [PubMed - indexed for MEDLINE]

7:

Differences in endogenous esterification and retention in the rat trachea between budesonide and ciclesonide active metabolite.

Lexmüller K, Gullstrand H, Axelsson BO, Sjölin P, Korn SH, Silberstein DS, Miller-Larsson A.

Drug Metab Dispos. 2007 Oct;35(10):1788-96. Epub 2007 Jul 12.

PMID: 17627977 [PubMed - indexed for MEDLINE]

9:

Reversible fatty acid conjugation of budesonide. Novel mechanism for prolonged retention of topically applied steroid in airway tissue.

Miller-Larsson A, Mattsson H, Hjertberg E, Dahlbäck M, Tunek A, Brattsand R.

Drug Metab Dispos. 1998 Jul;26(7):623-30.

PMID: 9660844 [PubMed - indexed for MEDLINE]

10:

Formation of fatty acid conjugates of ciclesonide active metabolite in the rat lung after 4-week inhalation of ciclesonide.

Nave R, Meyer W, Fuhst R, Zech K.

Pulm Pharmacol Ther. 2005;18(6):390-6.

PMID: 16179214 [PubMed - indexed for MEDLINE]

11:

Biotransformation of the topical glucocorticoids budesonide and beclomethasone 17 alpha,21-dipropionate in human liver and lung homogenate.

Andersson P, Ryrfeldt A.

J Pharm Pharmacol. 1984 Nov;36(11):763-5.

PMID: 6150981 [PubMed - indexed for MEDLINE]

12:

Ciclesonide versus other inhaled steroids for chronic asthma in children and adults.

Manning P, Gibson PG, Lasserson TJ.

Cochrane Database Syst Rev. 2008 Apr 16;(2):CD007031. Review.

PMID: 18425977 [PubMed - indexed for MEDLINE]

13:

The role of esterases in the metabolism of ciclesonide to desisobutyryl-ciclesonide in human tissue.

Mutch E, Nave R, McCracken N, Zech K, Williams FM.

Biochem Pharmacol. 2007 May 15;73(10):1657-64. Epub 2007 Jan 28.

PMID: 17331475 [PubMed - indexed for MEDLINE]

14:

Pharmacokinetics of butixocort 21-propionate, budesonide, and beclomethasone dipropionate in the rat after intratracheal, intravenous, and oral treatments.

Chanoine F, Grenot C, Heidmann P, Junien JL.

Drug Metab Dispos. 1991 Mar-Apr;19(2):546-53.

PMID: 1676668 [PubMed - indexed for MEDLINE]

16:

Comparative kinetics of metabolism of beclomethasone propionate esters in human lung homogenates and plasma.

Foe K, Brown KF, Seale JP.

J Pharm Sci. 2000 Sep;89(9):1143-50.

PMID: 10944379 [PubMed - indexed for MEDLINE]

17:

Uptake and metabolism of ciclesonide and retention of desisobutyryl-ciclesonide for up to 24 hours in rabbit nasal mucosa.

Sato H, Nave R, Nonaka T, Yoshihisa N, Atsuhiro N, Mochizuki T, Takahama S, Kondo S, Wingertzahn M.

BMC Pharmacol. 2007 Jun 6;7:7.

PMID: 17553148 [PubMed - indexed for MEDLINE]

18:

Lower oropharyngeal deposition of inhaled ciclesonide via hydrofluoroalkane metered-dose inhaler compared with budesonide via chlorofluorocarbon metered-dose inhaler in healthy subjects.

Nave R, Zech K, Bethke TD.

Eur J Clin Pharmacol. 2005 May;61(3):203-8. Epub 2005 Apr 12.

PMID: 15824911 [PubMed - indexed for MEDLINE]

19:

Improvement in health-related quality of life with fluticasone propionate compared with budesonide or beclomethasone dipropionate in adults with severe asthma.

Rutherford C, Mills R, Gibson PG, Price MJ.

Respirology. 2003 Sep;8(3):371-5.

PMID: 12911833 [PubMed - indexed for MEDLINE]

20:

Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children.

Adams N, Lasserson TJ, Cates CJ, Jones PW.

Cochrane Database Syst Rev. 2007 Oct 17;(4):CD002310. Review.

PMID: 17943772 [PubMed - indexed for MEDLINE]

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