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1:

Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.

Raoul W, Wagner-Ballon O, Saber G, Hulin A, Marcos E, Giraudier S, Vainchenker W, Adnot S, Eddahibi S, Maitre B.

Respir Res. 2007 Jan 30;8:8.

PMID: 17263874 [PubMed - indexed for MEDLINE]

2:

Bone marrow-derived cells contribute to pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension.

Hayashida K, Fujita J, Miyake Y, Kawada H, Ando K, Ogawa S, Fukuda K.

Chest. 2005 May;127(5):1793-8.

PMID: 15888860 [PubMed - indexed for MEDLINE]

3:

Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Sahara M, Sata M, Morita T, Nakamura K, Hirata Y, Nagai R.

Circulation. 2007 Jan 30;115(4):509-17. Epub 2007 Jan 22.

PMID: 17242277 [PubMed - indexed for MEDLINE]

4:

Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice.

Satoh K, Kagaya Y, Nakano M, Ito Y, Ohta J, Tada H, Karibe A, Minegishi N, Suzuki N, Yamamoto M, Ono M, Watanabe J, Shirato K, Ishii N, Sugamura K, Shimokawa H.

Circulation. 2006 Mar 21;113(11):1442-50. Epub 2006 Mar 13.

PMID: 16534010 [PubMed - indexed for MEDLINE]

5:

Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension.

Spees JL, Whitney MJ, Sullivan DE, Lasky JA, Laboy M, Ylostalo J, Prockop DJ.

FASEB J. 2008 Apr;22(4):1226-36. Epub 2007 Nov 21.

PMID: 18032636 [PubMed - indexed for MEDLINE]

6:

2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension.

Tofovic SP, Zhang X, Jackson EK, Dacic S, Petrusevska G.

Vascul Pharmacol. 2006 Dec;45(6):358-67. Epub 2006 Jun 8.

PMID: 16872912 [PubMed - indexed for MEDLINE]

7:

Autologous transplantation of bone marrow-derived endothelial progenitor cells attenuates monocrotaline-induced pulmonary arterial hypertension in rats.

Yip HK, Chang LT, Sun CK, Sheu JJ, Chiang CH, Youssef AA, Lee FY, Wu CJ, Fu M.

Crit Care Med. 2008 Mar;36(3):873-80.

PMID: 18431275 [PubMed - indexed for MEDLINE]

8:

Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.

Guignabert C, Izikki M, Tu LI, Li Z, Zadigue P, Barlier-Mur AM, Hanoun N, Rodman D, Hamon M, Adnot S, Eddahibi S.

Circ Res. 2006 May 26;98(10):1323-30. Epub 2006 Apr 13.

PMID: 16614302 [PubMed - indexed for MEDLINE]

9:

Sildenafil inhibits hypoxia-induced pulmonary hypertension.

Zhao L, Mason NA, Morrell NW, Kojonazarov B, Sadykov A, Maripov A, Mirrakhimov MM, Aldashev A, Wilkins MR.

Circulation. 2001 Jul 24;104(4):424-8.

PMID: 11468204 [PubMed - indexed for MEDLINE]

10:

Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

Steudel W, Scherrer-Crosbie M, Bloch KD, Weimann J, Huang PL, Jones RC, Picard MH, Zapol WM.

J Clin Invest. 1998 Jun 1;101(11):2468-77.

PMID: 9616218 [PubMed - indexed for MEDLINE]

11:

Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease.

Zhao YD, Courtman DW, Deng Y, Kugathasan L, Zhang Q, Stewart DJ.

Circ Res. 2005 Mar 4;96(4):442-50. Epub 2005 Feb 3.

PMID: 15692087 [PubMed - indexed for MEDLINE]

12:

Reduced hypoxic pulmonary vascular remodeling by nitric oxide from the endothelium.

Ozaki M, Kawashima S, Yamashita T, Ohashi Y, Rikitake Y, Inoue N, Hirata KI, Hayashi Y, Itoh H, Yokoyama M.

Hypertension. 2001 Feb;37(2):322-7.

PMID: 11230292 [PubMed - indexed for MEDLINE]

13:

Prolonged inhaled NO attenuates hypoxic, but not monocrotaline-induced, pulmonary vascular remodeling in rats.

Horstman DJ, Frank DU, Rich GF.

Anesth Analg. 1998 Jan;86(1):74-81.

PMID: 9428855 [PubMed - indexed for MEDLINE]

14:

Lung overexpression of angiostatin aggravates pulmonary hypertension in chronically hypoxic mice.

Pascaud MA, Griscelli F, Raoul W, Marcos E, Opolon P, Raffestin B, Perricaudet M, Adnot S, Eddahibi S.

Am J Respir Cell Mol Biol. 2003 Oct;29(4):449-57. Epub 2003 Apr 24.

PMID: 12714372 [PubMed - indexed for MEDLINE]

15:

Pulmonary artery remodeling differs in hypoxia- and monocrotaline-induced pulmonary hypertension.

van Suylen RJ, Smits JF, Daemen MJ.

Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1423-8.

PMID: 9603118 [PubMed - indexed for MEDLINE]

16:

The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS.

Guerard P, Rakotoniaina Z, Goirand F, Rochette L, Dumas M, Lirussi F, Bardou M.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Sep;373(6):401-14. Epub 2006 Aug 1.

PMID: 16896805 [PubMed - indexed for MEDLINE]

17:

Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling.

Chen YF, Feng JA, Li P, Xing D, Zhang Y, Serra R, Ambalavanan N, Majid-Hassan E, Oparil S.

J Appl Physiol. 2006 Feb;100(2):564-71. Epub 2005 Oct 13.

PMID: 16223981 [PubMed - indexed for MEDLINE]

18:

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice.

Song Y, Coleman L, Shi J, Beppu H, Sato K, Walsh K, Loscalzo J, Zhang YY.

Am J Physiol Heart Circ Physiol. 2008 Aug;295(2):H677-90. Epub 2008 Jun 13.

PMID: 18552156 [PubMed - indexed for MEDLINE]

19:

Deficiency of urokinase-type plasminogen activator-mediated plasmin generation impairs vascular remodeling during hypoxia-induced pulmonary hypertension in mice.

Levi M, Moons L, Bouché A, Shapiro SD, Collen D, Carmeliet P.

Circulation. 2001 Apr 17;103(15):2014-20.

PMID: 11306532 [PubMed - indexed for MEDLINE]

20:

Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension.

Case D, Irwin D, Ivester C, Harral J, Morris K, Imamura M, Roedersheimer M, Patterson A, Carr M, Hagen M, Saavedra M, Crossno J Jr, Young KA, Dempsey EC, Poirier F, West J, Majka S.

Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L154-64. Epub 2006 Sep 1.

PMID: 16951131 [PubMed - indexed for MEDLINE]

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