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1:

The safety and efficacy of inhaled dry powder mannitol as a bronchial provocation test for airway hyperresponsiveness: a phase 3 comparison study with hypertonic (4.5%) saline.

Brannan JD, Anderson SD, Perry CP, Freed-Martens R, Lassig AR, Charlton B; Aridol Study Group.

Respir Res. 2005 Dec 9;6:144.

PMID: 16336673 [PubMed - indexed for MEDLINE]

2:

Comparison of bronchial challenge with ultrasonic nebulized distilled water and hypertonic saline in children with mild-to-moderate asthma.

Wojnarowski C, Storm Van's Gravesande K, Riedler J, Eichler I, Gartner C, Frischer T.

Eur Respir J. 1996 Sep;9(9):1896-901.

PMID: 8880109 [PubMed - indexed for MEDLINE]

3:

[Comparison of sensitivity and specifity of two bronchial provocation tests with methacholine and hypertonic saline in bronchial hyperreactivity evaluation in asthmatics]

Piotrowska T, Siergiejko G, Siergiejko Z.

Pol Merkur Lekarski. 2007 Feb;22(128):126-9. Polish.

PMID: 17598657 [PubMed - indexed for MEDLINE]

4:

Responsiveness to mannitol in asthmatic subjects with exercise- and hyperventilation-induced asthma.

Brannan JD, Koskela H, Anderson SD, Chew N.

Am J Respir Crit Care Med. 1998 Oct;158(4):1120-6.

PMID: 9769270 [PubMed - indexed for MEDLINE]

5:

A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol.

Anderson SD, Brannan J, Spring J, Spalding N, Rodwell LT, Chan K, Gonda I, Walsh A, Clark AR.

Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):758-65.

PMID: 9309990 [PubMed - indexed for MEDLINE]

6:

Hypertonic saline challenge tests in the diagnosis of bronchial hyperresponsiveness and asthma in children.

Mai XM, Nilsson L, Kjellman NI, Björkstén B.

Pediatr Allergy Immunol. 2002 Oct;13(5):361-7.

PMID: 12431196 [PubMed - indexed for MEDLINE]

7:

Bronchial provocation tests: the rationale for using inhaled mannitol as a test for airway hyperresponsiveness.

Leuppi JD, Brannan JD, Anderson SD.

Swiss Med Wkly. 2002 Apr 6;132(13-14):151-8. Review.

PMID: 12070787 [PubMed - indexed for MEDLINE]

8:

Airway responsiveness to hypertonic saline: dose-response slope or PD15?

de Meer G, Marks GB, de Jongste JC, Brunekreef B.

Eur Respir J. 2005 Jan;25(1):153-8.

PMID: 15640337 [PubMed - indexed for MEDLINE]

9:

Methacholine dry powder inhaler as a new tool for bronchial challenge test.

Colombo G, Terzano C, Colombo P, Petroianni A, Ricci A, Buttini F.

Int J Pharm. 2008 Mar 20;352(1-2):165-71. Epub 2007 Dec 11.

PMID: 18055141 [PubMed - indexed for MEDLINE]

10:

Bronchial hyperresponsiveness to hypertonic saline challenge in children and adolescents.

Kussek P, Rosario Filho NA, Cat M.

J Bras Pneumol. 2006 May-Jun;32(3):195-201. English, Portuguese.

PMID: 17273607 [PubMed - indexed for MEDLINE]

11:

Repeatability of bronchial responsiveness to mannitol dry powder in children with asthma.

Barben J, Roberts M, Chew N, Carlin JB, Robertson CF.

Pediatr Pulmonol. 2003 Dec;36(6):490-4.

PMID: 14618640 [PubMed - indexed for MEDLINE]

12:

Effect of capsaicin on airway responsiveness to hypertonic saline challenge in asthmatic and non-asthmatic children.

Chang AB, Phelan PD, Holst D, Robertson CF.

Pediatr Pulmonol. 1997 Jun;23(6):412-6.

PMID: 9220522 [PubMed - indexed for MEDLINE]

13:

Asthmatic airway inflammation is more closely related to airway hyperresponsiveness to hypertonic saline than to methacholine.

Choi IS, Hong SN, Lee YK, Koh YI, Jang AS, Lee HC.

Korean J Intern Med. 2003 Jun;18(2):83-8.

PMID: 12872444 [PubMed - indexed for MEDLINE]

14:

Effects of single-dose zileuton on bronchial hyperresponsiveness in asthmatic patients treated with inhaled corticosteroids.

Dekhuijzen PN, Bootsma GP, Wielders PL, van den Berg LR, Festen J, van Herwaarden CL.

Eur Respir J. 1997 Dec;10(12):2749-53.

PMID: 9493655 [PubMed - indexed for MEDLINE]

15:

Relationship between airway hyperresponsiveness to mannitol and adenosine monophosphate.

Currie GP, Haggart K, Brannan JD, Lee DK, Anderson SD, Lipworth BJ.

Allergy. 2003 Aug;58(8):762-6.

PMID: 12859555 [PubMed - indexed for MEDLINE]

16:

Inhaled mannitol identifies methacholine-responsive children with active asthma.

Subbarao P, Brannan JD, Ho B, Anderson SD, Chan HK, Coates AL.

Pediatr Pulmonol. 2000 Apr;29(4):291-8.

PMID: 10738017 [PubMed - indexed for MEDLINE]

17:

Budesonide reduces sensitivity and reactivity to inhaled mannitol in asthmatic subjects.

Brannan JD, Koskela H, Anderson SD, Chan HK.

Respirology. 2002 Mar;7(1):37-44.

PMID: 11896899 [PubMed - indexed for MEDLINE]

18:

[Ultrasonically nebulized hypertonic saline as a provocation agent in asthmatics]

Sun B.

Zhonghua Jie He He Hu Xi Za Zhi. 1991 Apr;14(2):98-100, 128. Chinese.

PMID: 1879027 [PubMed - indexed for MEDLINE]

19:

Quantitative bronchial challenge tests with wheat flour dust administered by spinhaler: comparison with aqueous wheat flour extract inhalation.

Merget R, Heger M, Globisch A, Rasche K, Gillissen A, Gebler A, Schultze-Werninghaus G, Krieg M.

J Allergy Clin Immunol. 1997 Aug;100(2):199-207.

PMID: 9275141 [PubMed - indexed for MEDLINE]

20:

Airway hyperresponsiveness to hypertonic saline as a predictive index of exercise-induced bronchoconstriction.

Choi IS, Chung SW, Koh YI, Sim MK, Hong SN, Moon JS.

Korean J Intern Med. 2005 Dec;20(4):284-9.

PMID: 16491825 [PubMed - indexed for MEDLINE]

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