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Myosin phosphorylation and the cross-bridge cycle in arterial smooth muscle.

Dillon PF, Aksoy MO, Driska SP, Murphy RA.

Phosphorylation of the 20,000-dalton light chain of myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence is presented that dephosphorylation can produce an attached, noncycling cross-bridge (latch-bridge) which is responsible for the high economy of force maintenance in this tissue.

PMID: 6893872 [PubMed - indexed for MEDLINE]