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1.

1625
Accesses

Review   Open Access Highly Accessed

Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease

Donald P Tashkin, Gary T Ferguson Respiratory Research 2013, 14:49 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

1049
Accesses

Review   Open Access Highly Accessed

Idiopathic pulmonary fibrosis in 2011: key updates on guidelines and therapeutics Concluding remarks

Ulrich Costabel Respiratory Research 2013, 14(Suppl 1):S8 (16 April 2013)

Full text | PDF | ePUB

3.

1050
Accesses

Research   Open Access Highly Accessed

The Tiotropium Safety and Performance in Respimat® Trial (TIOSPIR®), a large scale, randomized, controlled, parallel-group trial-design and rationale

Robert A Wise, Antonio Anzueto, Peter Calverley, Ronald Dahl, Daniel Dusser, Gordon Pledger, Michael Koenen-Bergmann, Elizabeth Joseph, Daniel Cotton, Bernd Disse Respiratory Research 2013, 14:40 (2 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

1006
Accesses

Research   Open Access Highly Accessed

Role of exhaled nitric oxide as a predictor of atopy

Karina M Romero, Colin L Robinson, Lauren M Baumann, Robert H Gilman, Robert G Hamilton, Nadia N Hansel, William Checkley, PURA Study Investigators Respiratory Research 2013, 14:48 (2 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

889
Accesses

Review   Open Access Highly Accessed

Outcome measures in chronic obstructive pulmonary disease (COPD): strengths and limitations

Thomas Glaab, Claus Vogelmeier, Roland Buhl Respiratory Research 2010, 11:79 (17 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

6.

859
Accesses

Research   Open Access Highly Accessed

Impact of exacerbations of cystic fibrosis on muscle strength

Chris Burtin, Hans Van Remoortel, Bart Vrijsen, Daniel Langer, Kristine Colpaert, Rik Gosselink, Marc Decramer, Lieven Dupont, Thierry Troosters Respiratory Research 2013, 14:46 (19 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

844
Accesses

Review   Open Access Highly Accessed

The current position of surgical lung biopsy in the diagnosis of idiopathic pulmonary fibrosis

Riitta Kaarteenaho Respiratory Research 2013, 14:43 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

841
Accesses

Research   Open Access Highly Accessed

Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

Kristin Blidberg, Lena Palmberg, Anna James, Bo Billing, Elisabeth Henriksson, Ann-Sofie Lantz, Kjell Larsson, Barbro Dahlén Respiratory Research 2013, 14:47 (1 May 2013)

Abstract | Provisional PDF | PubMed

9.

808
Accesses

Research   Open Access Highly Accessed

Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency

Stephanie Korn, Marisa Hübner, Matthias Jung, Maria Blettner, Roland Buhl Respiratory Research 2013, 14:25 (22 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

786
Accesses

Review   Open Access

The role of pirfenidone in the treatment of idiopathic pulmonary fibrosis

Vincent Cottin Respiratory Research 2013, 14(Suppl 1):S5 (16 April 2013)

Abstract | Full text | PDF

11.

734
Accesses

Research   Open Access Highly Accessed

Critical role of aldehydes in cigarette smoke-induced acute airway inflammation

Marco Toorn, Dirk-Jan Slebos, Harold G de Bruin, Renee Gras, Delaram Rezayat, Lucie Jorge, Koen Sandra, Antoon JM Oosterhout Respiratory Research 2013, 14:45 (17 April 2013)

Abstract | Provisional PDF | PubMed

12.

734
Accesses

Research   Open Access Highly Accessed

The clinical features of the overlap between COPD and asthma

Megan Hardin, Edwin K Silverman, R Graham Barr, Nadia N Hansel, Joyce D Schroeder, Barry J Make, James D Crapo, Craig P Hersh, the COPDGene Investigators Respiratory Research 2011, 12:127 (27 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Subjects with COPD and asthma show unique clinical features such as increased respiratory exacerbations. Improved monitoring and prevention of exacerbations in these patients may improve quality of life and potentially survival.

13.

732
Accesses

Research   Open Access Highly Accessed

Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Uta Griesenbach, Chris Kitson, Sara Garcia, Raymond Farley, Charanjit Singh, Luci Somerton, Hazel Painter, Rbecca L Smith, Deborah R Gill, Stephen C Hyde, Yu-Hua Chow, Jim Hu, Mike Gray, Mark Edbrooke, Varrie Ogilvie, Gordon MacGregor, Ronald K Scheule, Seng H Cheng, Natasha J Caplen, Eric WFW Alton Respiratory Research 2006, 7:26 (15 February 2006)

Abstract | Full text | PDF | PubMed

14.

727
Accesses

Research   Open Access Highly Accessed

Current management of patients hospitalized with community-acquired pneumonia across Europe: outcomes from REACH

Francesco Blasi, Javier Garau, Jesús Medina, Marco Ávila, Kyle McBride, Helmut Ostermann, on behalf of the REACH study group Respiratory Research 2013, 14:44 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

15.

642
Accesses

Research   Open Access Highly Accessed

M2 macrophage polarisation is associated with alveolar formation during postnatal lung development

Christina V Jones, Timothy M Williams, Kenneth A Walker, Hayley Dickinson, Samy Sakkal, Bree A Rumballe, Melissa H Little, Graham Jenkin, Sharon D Ricardo Respiratory Research 2013, 14:41 (5 April 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

Macrophages are increased in number and display an M2 phenotype during alveolar development, which means modulation of macrophages could be a novel intervention for enhancing lung maturation.

16.

643
Accesses

Research   Open Access

Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury

Laura Amado-Rodríguez, Adrián González-López, Inés López-Alonso, Alina Aguirre, Aurora Astudillo, Estefanía Batalla-Solís, Jorge Blazquez-Prieto, Emilio García-Prieto, Guillermo M Albaiceta Respiratory Research 2013, 14:52 (10 May 2013)

Abstract | Provisional PDF | PubMed

17.

609
Accesses

Review   Open Access Highly Accessed

Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches

Osamu Matsuno Respiratory Research 2012, 13:39 (31 May 2012)

Abstract | Full text | PDF | PubMed

18.

600
Accesses

Research   Open Access Highly Accessed

Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD

Craig P Hersh, George R Washko, Raúl San José Estépar, Sharon Lutz, Paul J Friedman, MeiLan K Han, John E Hokanson, Philip F Judy, David A Lynch, Barry J Make, Nathaniel Marchetti, John D Newell, Frank C Sciurba, James D Crapo, Edwin K Silverman, The COPDGene Investigators Respiratory Research 2013, 14:42 (8 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

596
Accesses

Research   Open Access

The pulmonary effects of intravenous adenosine in asthmatic subjects

Nausherwan K Burki, Mahmud Alam, Lu-Yuan Lee Respiratory Research 2006, 7:139 (30 November 2006)

Abstract | Full text | PDF | PubMed

20.

596
Accesses

Research   Open Access

Complications associated with endobronchial ultrasound-guided transbronchial needle aspiration: a nationwide survey by the Japan Society for Respiratory Endoscopy

Fumihiro Asano, Motoi Aoe, Yoshinobu Ohsaki, Yoshinori Okada, Shinji Sasada, Shigeki Sato, Eiichi Suzuki, Hiroshi Semba, Kazuya Fukuoka, Shozo Fujino, Kazumitsu Ohmori Respiratory Research 2013, 14:50 (10 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

21.

595
Accesses

Review   Open Access Highly Accessed

The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis

Akos Somoskovi, Linda M Parsons, Max Salfinger Respiratory Research 2001, 2:164-168 (5 April 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

575
Accesses

Research   Open Access

Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust

Tara M Nordgren, Art J Heires, Todd A Wyatt, Jill A Poole, Tricia D LeVan, D Roselyn Cerutis, Debra J Romberger Respiratory Research 2013, 14:51 (10 May 2013)

Abstract | Provisional PDF | PubMed

23.

556
Accesses

Research   Open Access Highly Accessed

A mathematical reason for FEV1/FVC dependence on age

Tomasz Gólczewski, Wojciech Lubiński, Andrzej Chciałowski Respiratory Research 2012, 13:57 (4 July 2012)

Abstract | Full text | PDF | PubMed | 2 comments

24.

543
Accesses

Research   Open Access Highly Accessed

Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire

José Olaguibel, Santiago Quirce, Berta Juliá, Cristina Fernández, Ana Fortuna, Jesús Molina, Vicente Plaza, on behalf of the MAGIC Study Group Respiratory Research 2012, 13:50 (22 June 2012)

Abstract | Full text | PDF | PubMed

25.

527
Accesses

Review   Open Access

The revised ATS/ERS/JRS/ALAT diagnostic criteria for idiopathic pulmonary fibrosis (IPF) - practical implications

Athol U Wells Respiratory Research 2013, 14(Suppl 1):S2 (16 April 2013)

Abstract | Full text | PDF

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