|
Patient characteristics in the specimens examined by Western analysis. |
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| Non-smoker N = 7 |
Smoker N = 7 |
COPD N = 16 |
p-value |
|
|
|
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| Age, years |
63 (13) |
59 (4) |
62 (10) |
0.754 |
| Sex M:F |
4:3 |
5:2 |
12:4 |
0.688 |
| Pack-years |
0 |
36 (16)* |
34 (17)§ |
0.000 |
| FEV1 %predicted |
88 (18) |
88 (13) |
55 (31)*# |
0.005 |
| FEV1/FVC % |
83 (9) |
83 (10) |
57 (20)*# |
0.000 |
| MEF50 %pred |
88 (35) |
84 (61) |
37 (22) |
0.066 |
| DCO %pred |
95 (20) |
82 (10) |
52 (22)§ |
0.003 |
| DCO/VA %pred |
100 (18) |
89 (9) |
62 (24) § |
0.006 |
|
Mean (SD) All cases were studied for the expression of GST pi, but due to the exhaustion of biopsy material, only 4 non-smokers, 3 smokers and 8 COPD-cases were included in the Western analysis for GST alpha expression and 4 smokers, 4 non-smokers and 10 COPD-patients for GST mu expression. *The mean difference between non-smokers and smokers is significant at the 0.05 level, Dunnett t-test. § The mean difference between non-smokers and COPD-patients is significant at the 0.05 level, Dunnett t-test. # The mean difference between smokers and COPD-patients is significant at the 0.05 level, Dunnett t-test. | ||||
Harju et al. Respiratory Research 2008 9:80 doi:10.1186/1465-9921-9-80 |
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