Table 5

Mean (SE) FEV1 %predicted in relation to AAT quintile classes in non-current smokers†

Quintile classes of AAT (g/l)

Q0 (<0.9)
 Q1 (≥0.9–<1.13)
 Q2 (≥1.13, <1.22)
 Q3 (≥1.22, <1.31)
 Q4 (≥1.31, <1.41)
 Q5 (≥1.41)
 ptrend from model not including Q0
Men (n)
 66
 522
 439
 351
 226
 142
FEV1 (% predicted), CRP adj.
 99.5 (1.8)
 97.6 (0.6)
 97.9 (0.7)
 98.2 (0.8)
 97.0 (1.0)
 92.9 (1.3)
 0.05
FEV1 (% predicted), no CRP adj.*
 99.8 (1.8)
 98.1 (0.6)
 98.1 (0.6)
 98.0 (0.8)
 96.5 (0.9)
 91.9 (1.2)
 <0.001
Women (n)
64
 289
 282
 403
 315
 395
FEV1 (% predicted) CRP adj.
 101.0 (1.8)
 100.4 (0.9)
 99.8 (0.9)
 100.3 (0.7)
 99.9 (0.8)
 99.3 (0.8)
 0.85
FEV1 (% predicted), no CRP adj. *
 101.8 (1.8)
 100.9 (0.9)
 100.3 (0.9)
 100.4 (0.7)
 100.0 (0.8)
 98.4 (0.7)
 0.13
Premenopausal women (n)
27
 100
 109
 151
 131
 187
FEV1 (% predicted), CRP adj.
 98.7 (2.4)
 98.3 (1.3)
 97.2 (1.2)
 99.6 (1.0)
 101.5 (1.1)
 99.7 (1.0)
 0.02
FEV1 (% predicted), no CRP adj.*
 99.1 (2.4)
 98.8 (1.3)
 97.1 (1.0)
 99.6 (1.0)
 101.7 (1.1)
 99.1 (1.0)
 0.11
Postmenopausal women (n)
37
 189
 173
 252
 184
 208
FEV1 (% predicted), CRP adj.
 102.5 (2.5)
 101.5 (1.1)
 101.5 (1.2)
 100.8 (1.0)
 98.8 (1.1)
 98.7 (1.1)
 0.04
FEV1 (% predicted), no CRP adj.*
 103.4 (2.5)
 102.1 (1.1)
 101.7 (1.1)
 101.0 (1.0)
 98.7 (1.1)
 97.7 (1.1)
 <0.001

† adjusted for BMI, passive smoking, years since quitting, systolic blood pressure, alcohol consumption, study area, CRP, CRP2 (models with CRP); * adjusted for all covariates but CRP; ¶additionally adjusted for menopausal status, intake of female hormones; women in perimenopausal status (n = 35) and missing/unclear status and hormonal intake (n = 120) were excluded;

Senn et al. Respiratory Research 2008 9:35   doi:10.1186/1465-9921-9-35