|
Densitometric progression adjusted for lung volume using linear regression |
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| Variable |
Linear regression models |
Intercept, mean ± SE (95% CI) |
t |
p value |
Annual change |
|
|
|||||
| WL Perc15 |
ΔPCP = -12.12*ΔCTVol -3.57 |
-3.57 ± 0.83 (-5.48, -1.65) |
-3.72 |
0.0004 |
-1.79 |
| WL VI-950 |
ΔVI-950 = 2.54* ΔCTVol + 1.94 |
1.94 ± 0.44 (1.07, 2.81) |
4.45 |
< 0.0001 |
0.97 |
| WL VI-910 |
ΔVI-910 = 6.58* ΔCTVol + 2.28 |
2.28 ± 0.57 (1.15, 3.42) |
4.01 |
0.0002 |
1.14 |
|
WL, whole lung; Perc15, 15th percentile point (measured in Hounsfield Units); VI-950, voxel index at a threshold of -950HU (measured in %); VI-910, voxel index at a threshold of -910HU (measured in %); Δ, change over study period; SE, standard error; 95% CI, 95% confidence interval; annual change, change outcome measure from baseline to follow-up incorporating adjustment for lung volume, estimated from the intercept (ΔCTVol = 0). | |||||
Parr et al. Respiratory Research 2008 9:21 doi:10.1186/1465-9921-9-21 |
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