Table 1

Effect of mAbs on ability of SP-D to inhibit viral hemagglutination activity

MAb added:
None
245-01a
246-04
246-07

HA inhibiting conc. of SP-D
(ng/ml)b
49 ± 14
37 ± 11
55 ± 17
>420
p < 0.001

a Recombinant human SP-D multimers were pre-incubated with the indicated MAbs prior to adding SP-D to virus and assaying HA inhibition.

b The values shown are mean ± SEM (n = 4) amounts of SP-D needed to inhibit 40 HA units of the Phil82 strain of IAV.

Hartshorn et al. Respiratory Research 2007 8:9   doi:10.1186/1465-9921-8-9