Low power light micrographs (methylene blue stained sections) from lungs of (A) group D0, (B) group D3, (C) group D6, (D) group D9 and (E) group WT. In contrast to untreated knock-out mice (A) the lungs of treated groups (B-D) demonstrate, compared to group WT (E), almost normal lung architecture with no major differences among them. In A an accumulation of intraalveolar surfactant (short arrow) and some foamy alveolar macrophages (long arrows) are visible.
Knudsen et al. Respiratory Research 2007 8:70 doi:10.1186/1465-9921-8-70