Figure 1.

Mean amounts of parent compounds and metabolites in lung tissue slices over time. Initial substrate concentration: 25 μM. ¹Sum of analytes = Pool for active drug detectable in human lung slices after 2, 6, and 24 h of incubation. BDP = beclomethasone dipropionate, BUD = budesonide, CIC = ciclesonide, FP = fluticasone propionate.