Figure 3.

A-D. INH-treated TST⁺ subjects with a past MTB exposure: time course of M.tuberculosis-specific immune response. Responses to PPD (A), QTF-G (B), RD1 intact proteins (C), and RD1 selected peptides (D) in TST⁺ contacts that underwent INH therapy were evaluated over time at time 1 (baseline), time 2 (after 1–2 months of INH therapy), time 3 (therapy completion) and no statistically significant changes were recorded. PPD: purified protein derivative; RD: region of difference; QTF-G: QuantiFERON TB Gold; IFN: interferon; IU: international units.