|
Cellular localization and functions of genes regulated by V2O5 grouped by functional categories (See Fig. 3). |
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| Accession#a |
Gene Symbol |
Gene Name |
Localization |
Function |
|
|
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| Cytokines and Chemokines |
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| Hs.512234 |
IL6 |
lnterleukin-6 (interferon beta2) |
Secreted |
Inflammation |
| Hs.624 |
IL8 |
lnterleukin-8 |
Secreted |
Neutrophil Chemotaxis |
| Hs. 168132 |
IL15 |
lnterleukin-15 |
Secreted |
T Lymphocyte Proliferation |
| Hs.271387 |
CCL8 |
CC Chemokine Ligand 8 |
Secreted |
Neutrophil Chemotaxis |
| Hs.77367 |
CXCL9 |
Chemokine (C-X-C motif) Ligand 9 (Mig) |
Secreted |
Inflammation |
| Hs.632586 |
CXCL10 |
Chemokine (C-X-C motif) Ligand 10 (IP-10) |
Secreted |
Inflammation |
| Growth Factors |
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| Hs.73793 |
VEGF |
Vascular Endothelial Cell Growth Factor |
Secreted |
Endothelial Cell Growth |
| Hs.396530 |
HGF |
Hepatocyte Growth Factor |
Secreted |
Epithelial Cell Growth |
| Hs.799 |
HBEGF |
Heparin-Binding EGF-like Growth Factor |
Membrane/Secreted |
Fibroblast Growth |
| Hs.591346 |
CTGF |
Connective Tissue Growth Factor |
Secreted |
Collagen Synthesis |
| Hs.111 |
FGF9 |
Fibroblast Growth Factor-9 |
Membrane/Secreted |
Fibroblast Growth |
| Hs.284244 |
FGF2 |
Fibroblast Growth Factor-2 |
Membrane/Secreted |
Fibroblast Growth |
| STAT Signaling |
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| Hs.591081 |
JAK2 |
Janus Activated Kinase-2 |
Membrane |
STAT Phosphorylation |
| Hs.436061 |
IRF1 |
Interferon-Regulatory Factor-1 |
Cytoplasmic/Nuclear |
Transcriptional Regulation |
| Hs.527973 |
SOCS3 |
Suppressor of Cytokine Signaling-3 |
Cytoplasmic |
Cell Signaling |
| Hs.50640 |
SOCS1 |
Suppressor of Cytokine Signaling-1 |
Cytoplasmic |
Cell Signaling |
| Hs.470943 |
STAT1 |
Signal Transducer Activator of Transcription |
Cytoplasmic |
Growth Arrest and Apoptosis |
| Hs.520414 |
IFNGR1 |
Interferon Gamma Receptor- 1 |
Membrane |
Cell Signaling |
| Cell Cycle Regulation |
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| Hs.238990 |
CDKN1B |
Cyclin-Dependent Kinase lnhbitior-1B (Kip1) |
Nuclear |
Cell Cycle Arrest |
| Hs. 106070 |
CDKN1C |
Cyclin-Dependent Kinase lnhibitor-1C (Kip2) |
Nuclear |
Cell Cycle Arrest |
| Hs.525324 |
CDKN2C |
Cyclin-Dependent Kinase lnhibitor-2C |
Nuclear |
Cell Cycle Arrest |
| Hs.557646 |
CDK9 |
Cyclin-Dependent Kinase-9 |
Nuclear |
Transcriptional Regulation |
| Hs. 184298 |
CDK7 |
Cyclin-Dependent Kinase-7 |
Nuclear |
Transcriptional Regulation |
| Hs. 13291 |
CCNG2 |
Cyclin G2 |
Nuclear |
Cell Cycle Arrest |
| Oxidative Stress |
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| Hs.475970 |
OXSR1 |
Oxidative Stress Response 1 |
Cytoplasmic |
Intracellular Kinase |
| Hs.487046 |
SOD2 |
Superoxide Dismutase 2 (SOD2) |
Cytoplasmic |
Peroxide Generation |
| Hs. 148778 |
OXR1 |
Oxidative Resistance 1 |
Cytoplasmic |
Anti-Oxidant |
| Hs.462585 |
PIPOX |
Pipecolic Acid Oxidase |
Cytoplasmic |
Peroxide Generation |
| Hs.465870 |
KEAP1 |
Kelch-like ECH-associated protein 1 |
Cytoplasmic |
Redox Homeostasis |
| Hs.406515 |
NQO1 |
NAD(P)H:quinone oxidoreductase 1 |
Cytoplasmic |
Redox Homeostasis |
| TGF-beta Signaling and Collagen |
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| Hs. 133379 |
TGFB2 |
Transforming Growth Factor beta-2 |
Secreted |
Matrix Synthesis, Immunity |
| Hs.519005 |
SMAD1 |
mothers against DPP homolog 1 |
Cytoplasmic |
Cell Signaling |
| Hs. 189329 |
SMURF1 |
Smad Ubiquitin Regulatory Factor-1 |
Cytoplasmic |
Cell Signaling |
| Hs.489142 |
COL1A2 |
Collagen 1A2 |
Secreted |
Structural Protein |
| Hs. 172928 |
COL1A1 |
Collagen 1A1 |
Secreted |
Structural Protein |
| Hs.443625 |
COL3A1 |
Collagen 3A1 |
Secreted |
Structural Protein |
|
aGene annotations are from NCBI http://www.ncbi.nlm.nih.gov. | ||||
Ingram et al. Respiratory Research 2007 8:34 doi:10.1186/1465-9921-8-34 |
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