|
Temporal expression categories of selected genes significantly induced or suppressed by V2O5 exposure and their cellular localization and functions (See Fig. 2). |
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| Accession#a |
Gene Symbol |
Gene Name |
Localization |
Function |
|
|
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| Progressively Induced Genes |
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| Hs.25590 |
STC1 |
Stanniocalcin |
Secreted |
Cellular Metabolism |
| Hs.448611 |
PBEF1 |
Pre-B Cell Colony Enhancing Factor 1 |
Secreted |
Inflammation |
| Hs.78913 |
CX3CR1 |
Chemokine (C-X3-C motif) Receptor 1 |
Membrane |
Inflammation |
| Hs.515258 |
GDF15 |
Growth and Differentiation Factor-15 |
Secreted |
Growth Inhibition |
| Hs.471221 |
KLF7 |
Kruppel-like factor 7 |
Nuclear |
Transcriptional Regulation |
| Hs.525704 |
JUN |
V-jun sarcoma virus 17 oncogene |
Nuclear |
Transcriptional Regulation |
| Progressively Suppressed Gene |
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| Hs.65029 |
GAS1 |
Growth Arrest Specific Gene 1 |
Nuclear |
Growth Arrest and Apoptosis |
| Hs.519162 |
BTG2 |
B-Cell Translocation Gene 2 |
Nuclear |
Growth Arrest |
| Hs.255935 |
BTG1 |
B-Cell Translocation Gene 1 |
Nuclear |
Growth Arrest |
| Hs.8375 |
TRAF4 |
TNF Receptor-Associated Factor |
Membrane |
Inflammation/Immunity |
| Hs. 109225 |
VCAM1 |
Vascular Cell Adhesion Molecule 1 |
Membrane |
Cell Adhesion |
| Hs.519909 |
MARCKS |
Myristolated Alanine-rich C Kinase Substrate |
Cytoplasmic |
Cell Signaling |
| Early Induced I/Late Suppressed Genes |
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| Hs.298654 |
DUSP6 |
MAP kinase phosphatase 3 |
Cytoplasmic |
Cell Signaling |
| Hs.532411 |
LYST |
Lysosomal Trafficking Regulator Gene |
Cytoplasmic |
Cell Signaling |
| Hs.514746 |
GATA6 |
GATA6 Transcription Factor |
Nuclear |
Transcriptional Regulation |
| Hs.37982 |
NEDD9 |
Neural expressed Develop. down-regulated 9 |
Membrane |
Cell Adhesion |
| Hs.502328 |
CD44 |
CD44 molecule (Indian blood group) |
Membrane |
Cell Signaling |
| Hs.59332 |
SPRED2 |
Sprouty-Related EVH Domain-2 |
Cytoplasmic |
Cell Signaling |
| Biphasic Induced Genes |
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| Hs.326035 |
EGR1 |
Early Growth Response-1 Gene |
Cytoplasmic/Nuclear |
Transcriptional Regulation |
| Hs.534313 |
EGR3 |
Early Growth Response-3 Gene |
Cytoplasmic/Nuclear |
Transcriptional Regulation |
| Hs.73853 |
BMP2 |
Bone Morphogenic Protein-1 |
Secreted |
Cell Differentiation |
| Hs.591241 |
CCNT2 |
Cyclin T2 |
Nuclear |
Cell Cycle Regulation |
| Hs.62661 |
GBP1 |
guanylate-binding protein 1, IFN-inducible |
Cytoplasmic |
Antiviral Activitiy |
| Hs.419240 |
SLC2A3 |
Solute Carrier Family 2 (GLUT3) |
Membrane |
Metabolism |
|
aGene annotat ions are from NCBI http://www.ncbi.nlm.nih.gov. | ||||
Ingram et al. Respiratory Research 2007 8:34 doi:10.1186/1465-9921-8-34 |
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