Figure 1.

Heatmap showing hierarchical clustering of human lung fibroblast genes significantly induced (RED) or suppressed (GREEN) by V₂O₅ treatment. Gene expression in response to V₂O₅ was considered significant if p-value ≤ 0.05 and exhibited ≥ 2-fold change over untreated control. Left panel: All genes changed more than 2-fold. Panels A and B: Representative clusters of genes progressively induced. Panel C: Representative cluster of genes induced in a biphasic manner. Panel D: Representative cluster of suppressed genes. Panel E: Representative clusters of genes induced early then suppressed late.