Figure 4.

Reduction of IL-18 levels in the BALF of rats instilled and injected with anti IL-18 or control IgG₁, then instilled with LPS and sacrificed 2, 4 and 8 d post instillation. BALF was obtained from IL-18-depleted and control rats as described above and IL-18 was determined using Luminex 100 technology. n = 3–6 rats per group. * = statistically different from controls treated with IgG₁ (P < 0.05).