Table 1

List of studied angiogenic and angiostatic mediators in ILDs

Angiogenic mediators

CXC chemokines containing the ELR motif
     • GRO-a/CXCL1
     • GRO-b/CXCL2
     • GRO-γ/CXCL3
     • ENA-78/CXCL5
     • GCP-2/CXCL6
     • NAP-2/CXCL7
     • IL-8/CXCL8

Growth Factors
     • VEGF
     • bFGF

Angiostatic mediators

CXC chemokines that lack the ELR motif
     • PF-4/CXCL4
     • MIG/CXCL9
     • IP-10/CXCL10
     • ITAC/CXCL11
     • CXCL14

Growth Factors
     • PEDF
Abbreviations: bFGF: basic fibroblast growth factor, GCP: Granulocyte chemotactic protein, GRO: Growth related genes, IP-10:IFN-γ-inducible -protein 10, ITAC: IFN-γ-inducible T-cell a chemoattractant, MIG: Monocyte Induced by interferon gamma-protein, NAP: Neutrophil activating protein, PEDF: Pigment epithelium growth factor, PF: Platelet factor,, VEGF: Vascular growth factor

Tzouvelekis et al. Respiratory Research 2006 7:82   doi:10.1186/1465-9921-7-82

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