Figure 2.

Cytokine release from infected HASM cells. A and C cytokine release in response to rhinovirus infection of HASM cells derived from non-asthmatic (open bars) and asthmatic (black bars) subjects, measured in the cell free tissue culture supernatant 24 hours post infection. B and D Stimulation of HASM cells with 5% FBS and concurrent RV infection. No significant difference was observed between IL-6 and IL-8 output in response to FBS stimulation between HASM cells derived from asthmatic and non-asthmatic volunteers. IL-6 and IL-8 were induced in both cell types in response to stimulation with 5% FBS, and concurrent infection with RV in the presence of 5% FBS induced IL-6 and IL-8 release in the non-asthmatic cells, and IL-8 in the non-asthmatic cells. # p = 0.05 0.1% FBS versus 5%FBS, * p < 0.05 0.1% FBS versus 5%FBS, *** p < 0.001 0.1% FBS versus 5%FBS, the P value indicates the level of significance between 5%FBS and 5%FBS + RV.