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Biochemical analysis of bronchoalveolar lavage fluid at 24 h of different gas exposure. |
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| Subgroup |
TPL (mg/kg) |
DSPC (mg/kg) |
TP (mg/kg) |
DSPC/TP (μg/mg) |
|
|
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| C-Air |
7.8 ± 1.6 |
3.4 ± 0.4 |
19.2 ± 04.9 |
186 ± 38.9 |
| LPS-Air |
6.3 ± 1.6 * |
2.7 ± 0.7 ** |
29.9 ± 6.0 # |
89 ± 12.4 ##** |
| C-ONO |
7.4 ± 2.0 |
3.3 ± 0.5 |
18.0 ± 3.8 |
188 ± 22.9 |
| LPS-ONO |
5.4 ± 1.2 |
2.2 ± 0.7 |
38.3 ± 12.0 ## |
63 ± 20.3 ##* |
| C-O |
8.1 ± 1.2 |
3.3 ± 0.6 |
19.8 ± 6.3 |
176 ± 33.4 |
| LPS-O |
4.1 ± 0.8 ## |
1.6 ± 0.4 ## |
46.2 ± 8.8 ## |
35.0 ± 3.8 ## |
| C-NO |
7.8 ± 1.8 |
3.5 ± 0.7 |
20.2 ± 6.6 |
179 ± 31.0 |
| LPS-NO |
5.9 ± 1.6 |
2.5 ± 0.8 |
33.2 ± 6.8 ## |
75 ± 14.7 ##** |
|
Definition of subgroups and parameter abbreviations: C, normal control group; LPS, lipopolysaccharides-treated group; Air, room air; NO, 20 ppm nitric oxide; ONO, 95% O2 and 20 ppm NO; O, 95% O2. TPL, total phospholipids; DSPC/TPL, disaturated phosphatidylcholine to TPL ratio; TP, total proteins; DSPC/TP, DSPC to TP ratio. Values represent means ± SD (n = 8). Statistical analysis: # P < 0.05, ## P < 0.01 versus the corresponding C subgroup; * p < 0.05, ** p < 0.01 versus LPS-O. | ||||
Gong et al. Respiratory Research 2006 7:5 doi:10.1186/1465-9921-7-5 |
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