Figure 1.

Increased serum and bronchoalveolar lavage fluid TNFα, MIP-2 and CCL2 levels in mice in response to intraperitoneal endotoxin application. Mice were either left untreated (0 h time points) or received a single intraperitoneal endotoxin application (50 μg/mouse). At various time points thereafter, mice were sacrificed and serum (A) and BAL fluid (B) TNFα (black bars), MIP-2 (grey bars) and CCL2 (white bars) levels were quantified by ELISA. The values are shown as mean ± SEM of 4–6 independent experiments. * indicates p < 0.01 versus respective control (0 h).