Figure 2.

Effect of pharmacological leukotrienes activity inhibition on lung myeloperoxidase. Immunohistochemical localization of myeloperoxidase in the lung. A: Bleomycin alone in WT mice. B: Bleomycin in MK-571 treated mice. C: Bleomycin in Zileuton treated mice. Original magnification: 150×. Each image is representative of at least 3 experiments. D: Effect of pharmacological leukotrienes activity inhibition on lung myeloperoxidase activity. Black bar represents control group, grey bar MK-571 group and white bar Zileuton group. Data are means ± SEM from 15 mice for each group. *p < 0.01 versus sham. °p < 0.01 vs. bleomycin.