Figure 4.

Cigarette smoke extract caused necrosis with no or little evidence of apoptosis in human lung epithelial cell from papillary adenocarcinoma patient (H441). Human lung epithelial cell from papillary adenocarcinoma patient (H441) were treated with media alone (control) and various concentrations of CSE; a) control, b) CSE (1.0%), c) CSE (2.5%), d) CSE (5.0%), e) CSE (7.5%), f) CSE (10%) for 24 hr. Results are mean of 3 experiments ± SEM. ^#p < 0.01, and ^§p < 0.001 compared with control group. L = Live; A = Apoptosis; N = Necrosis.