Table 2

Flow cytometric analysis of HLA class II expression on nasal epithelial cells.

Human nasal epithelial cells
% positive
Mean fluorescence

Normal
2.5 ± 0.63
205 ± 40
Normal + IFN-γ
10.2 ± 2.69
1145 ± 301
Asthmatic
2.03 ± 0.47
193 ± 37
Asthmatic + IFN-γ
11.76 ± 1.87
1013 ± 189

Nasal epithelial cells were detached from culture dishes by means of nonenzymatic cell dissociation solution and were then stained with anti-HLA-DR, P, Q, FITC-conjugated monoclonal antibody. Membrane fluorescence was analysed by flow cytometry.

O'Brien et al. Respiratory Research 2006 7:115   doi:10.1186/1465-9921-7-115