Figure 3.

Histological analysis of mouse lung sections after theophylline treatment: (a) negative control, (b) untreated (OVA-challenged), (c) unmodified ('pure') chitosan nanoparticles, (d) Thiolated chitosan, (e) theophylline, (f) theophylline plus unmodified chitosan nanoparticles, (g) theophylline plus TCNs. On day 22, lungs were removed, sectioned and stained with hematoxylin/eosin. Examination of tissue sections was performed by different persons in a blinded fashion. The results of a representative experiment of 3 slides for each section are shown.