Figure 6.

Effect of the pretreatment with the PKC inhibitor GF109203X on salbutamol-induced relaxation in challenged human bronchial rings. Relaxant responses to salbutamol in five carbachol-contracted human bronchial rings. Values of 100 and 0 on y-axis represent maximal force in response to 10^-6M carbachol and minimal force at 10^-4M salbutamol, respectively. ■, challenged-untreated rings; ○, rings pre-treated with 10^-7M GF109203X; ▲, ring pre-treated with 10^-6M GF109203X.