Study design. All animals were immunized with OVA and 14 days later exposed to aerosol challenge with OVA for 7 days to establish tissue and lumen eosinophilia. Treatment with anti-Fas mAb or isotype control IgG was administered intra-nasally at day 22 and outcome measurements including BAL and tissue sampling were made at 8 and 24 h after treatment.
Uller et al. Respiratory Research 2005 6:90 doi:10.1186/1465-9921-6-90