|
Quality of life as assessed on the St George's Hospital Respiratory |
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| Losartan |
Placebo |
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|
|
|||||||
| Baseline (n = 19) |
End of study (n = 15) |
Change |
Baseline (n = 20) |
End of study (n = 18) |
Change |
p-value* |
|
|
|
|||||||
| Overall score |
66 (18) |
60 (15) |
-3.6 (9.2) |
65 (14) |
66 (19) |
+1.7 (9.2) |
0.11 |
| Symptom component |
72 (17) |
67 (22) |
-2.7 (15.5) |
71 (16) |
66 (20) |
-5.6 (16.3) |
0.61 |
| Activity component |
76 (17) |
74 (13) |
-1.2 (10.8) |
77 (17) |
83 (19) |
+7.5 (14.1) |
0.06 |
| Impact component |
57 (23) |
49 (18) |
-5.2 (12.6) |
56 (17) |
56 (22) |
+0.7 (13.1) |
0.20 |
|
*Between group p-value for the difference in change from baseline. NB. Improvement in QoL is denoted by a reduction in score. | |||||||
Morrell et al. Respiratory Research 2005 6:88 doi:10.1186/1465-9921-6-88 |
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