Figure 2.

Histological appearance of C57 BI/6 mouse lungs 3 and 7 days following bleomycin challenge. (A) Histologic section from the lung of a C57 Bl/6 mouse treated with saline showing a normal parenchyma. Representative histologic sections of C57 Bl/6 mice at 3 (B) and 7 (C and D) days after bleomycin treatment showing appreciable morphologic emphysema but not fibrosis. Scattered inflammatory cells are present through lung parenchyma (E). (E) Shows a higher magnification of (D). (A-C): Hematoxylin-eosin stain, scale bar represents 400 μm. (D) and (E): Masson's trichrome stain, original magnification × 40 and × 100, respectively. Scale bars represent 400 μm and 100 μm, respectively.