Table 1

List of studied serum biomarkers in ARDS

Lung epithelium-specific proteins
Surfactant-associated proteins

• SP-A

• SP-B

• SP-D



Mucin-associated antigens

• KL-6/MUC1


Cytokines
• IL-1

• IL-2

• IL-6

• IL-8

• IL-10

• IL-15

• TNFa


Other serological parameters
Markers of endothelium activation

• Adhesion molecules (E, L-selectin, I-CAM-1, V-CAM-1)

• VWF



Markers of neutrophil activation

• MMP-9

• LTB4

Ferritin

Abbreviations: ARDS: Acute Respiratory Distress Syndrome, CC16: Clara-cell protein 16, IL: Interleukin, KL-6: Krebs von den Lungen-6, LTB4: Leukotriene B4 MMP-9: Metalloproteinase-9 MUC: Mucin, I-CAM-1: Intercellular Adhesion Molecule-1, sIL-2R: soluble interleukin-2 receptor, V-CAM-1: Vascular Adhesion Molecule-1, VWF: von Willebrand factor antigen

Tzouvelekis et al. Respiratory Research 2005 6:62   doi:10.1186/1465-9921-6-62