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Serum biomarkers in Acute Respiratory Distress Syndrome an ailing prognosticator

Argyris Tzouvelekis1 email, Ioannis Pneumatikos2 email and Demosthenes Bouros2 email

1Interstitial Lung Disease Unit, Royal Brompton Hospital, Imperial College, Faculty of Medicine London, UK

2Department of Pneumonology, Medical School, Democritus University of Thrace, Greece

author email corresponding author email

Respiratory Research 2005, 6:62doi:10.1186/1465-9921-6-62

Published: 22 June 2005

Abstract

The use of biomarkers in medicine lies in their ability to detect disease and support diagnostic and therapeutic decisions. New research and novel understanding of the molecular basis of the disease reveals an abundance of exciting new biomarkers who present a promise for use in the everyday clinical practice. The past fifteen years have seen the emergence of numerous clinical applications of several new molecules as biologic markers in the research field relevant to acute respiratory distress syndrome (translational research). The scope of this review is to summarize the current state of knowledge about serum biomarkers in acute lung injury and acute respiratory distress syndrome and their potential value as prognostic tools and present some of the future perspectives and challenges.


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