Morphological changes induced by TGF-β1. A549 cells were incubated with 5 ng/ml of TGF-β1 for 48 h. (A) Untreated A549 cells show a pebble-like shape and cell-cell adhesion is clearly observed. (B) TGF-β1-treated cells show a decrease in cell-cell contacts and adopt a more elongated morphological shape (magnification of 200×).
Kasai et al. Respiratory Research 2005 6:56 doi:10.1186/1465-9921-6-56