Effect of indomethacin and H-89 on ATP-induced contraction in rat isolated airway rings. A: Fmax to 10-3 M ATP in rat airway rings in the presence of 10 μM indomethacin. Horizontal bars are Fmax in control conditions. B: TR10 in rat airway rings stimulated by 10-3 M ATP in the presence of 10 μM indomethacin (n = 5 to 8) C: TR10 in rat airway rings stimulated by 10-3 M ATP in the presence of H-89 (n = 8). Trachea: black column; left (LEPB) and right EPB (REPB): hatched columns; left IPB: cross-hatched column. Vertical bars are TR10 in control conditions. Error bars are SEM. *P < 0.05.
Mounkaïla et al. Respiratory Research 2005 6:143 doi:10.1186/1465-9921-6-143