Table 1

Cellular profile in bronchoalveolar lavage fluid.
Group
 Animals (n)
 Total Cells (× 104/total BAL)
 Macrophages (× 104/total BAL)
 Eosinophils (× 104/total BAL)
 Neutrophils (× 104/total BAL)
 Mononuclear Cells (× 104/total BAL)
vehicle
 16
 36.88 ± 3.56
 36.74 ± 3.53
 0 ± 0
 0.12 ± 0.05
 0.015 ± 0.01
14 nm
 13
 111.69 ± 9.27**
 83.79 ± 6.03**
 0.332 ± 0.176
 27.04 ± 4.98**
 0.491 ± 0.201*
56 nm
 14
 97.36 ± 16.06**
 88.64 ± 15.34**
 0.331 ± 0.177
 8.09 ± 2.49*
 0.265 ± 0.093
OVA
 16
 85.06 ± 12.63**
 81.91 ± 12.4**
 0.705 ± 0.255
 2.2 ± 0.62
 0.121 ± 0.059
OVA + 14 nm
 16
 193.69 ± 18.33** ## $$
 141.86 ± 14.97** ## $
 13.667 ± 4.731** ## $
 36.9 ± 3.67** ## $
 0.878 ± 0.232** #
OVA + 56 nm
 17
 102.65 ± 11.64**
 90.7 ± 10.12**
 3.984 ± 2.669
 7.79 ± 2.29*
 0.204 ± 0.073

Six groups of mice were intratracheally administered with vehicle, ovalbumin (OVA), nano particles, or combinations of OVA and nano particles for 6 wk. Bronchoalveolar lavage (BAL) was conducted 24 h after the last intratracheal instillation. Total cell counts were determined on fresh BAL fluid, and differential cell counts were assessed with Diff-Quik-staining. Results are presented as mean ± SEM. *P < 0.05 versus vehicle, **P < 0.01 versus vehicle, #P < 0.05 versus OVA, ##P < 0.01 versus OVA. $P < 0.05 versus nano particles. $$P < 0.01 versus nano particles.

Inoue et al. Respiratory Research 2005 6:106   doi:10.1186/1465-9921-6-106