Figure 1.

RANTES and eotaxin released from A549 cells. Melatonin(10^-6M) alone did not change RANTES and eotaxin released from A549 cells. However, it (from10^-10 to 10^-6M) promoted RANTES and eotaxin released from A549 cells in a dose dependent manner when co-stimulated with TNF-α (100 ng/ml). * and **, p < 0.05 and 0.01, compared with control and melatonin alone (pg/ml, n = 3). $ and #, p < 0.05 and 0.01, compared with TNF-α alone (pg/ml, n = 3).