Failure of inhaled heparin disaccharide to inhibit allergic bronchoconstrictor responses in sheep. Top: Antigen-induced % change in specific lung resistance (SRL) ± SE in "Acute Responders" with (4 mg/kg; n = 3) and without pretreatment (control). Bottom: "Dual Responders" (1 mg/kg, n = 3,) without (control; open circles) and after treatment (solid circles) with inhaled disaccharide.
Ahmed et al. Respiratory Research 2012 13:6 doi:10.1186/1465-9921-13-6