Table 1

Differential cell counts (expressed as cells × 104) in BALF from mice subjected to LPS-induced ALI following different treatments
Treatment group Time after LPS induction of ALI
6 h 12 h 24 h
Macrophages Neutrophils Lymphocytes Macrophages Neutrophils Lymphocytes Macrophages Neutrophils Lymphocytes
Saline 15.43 ± 6.80 0.03 ± 0.04 0.55 ± 0.42 22.10 ± 7.10 0.07 ± 0.07 0.50 ± 0.66 25.25 ± 7.99 0.22 ± 0.05 0.53 ± 0.03
RvD1 (600 ng) 21.25 ± 8.89 0.42 ± 0.72 1.00 ± 0.31 22.34 ± 3.70 0.33 ± 0.42 1.33 ± 0.61 28.44 ± 4.29 0.18 ± 0.19 1.71 ± 1.10
LPS 15.07 ± 3.35 128.89 ± 6.45 2.37 ± 0.69 15.83 ± 4.71 162.73 ± 4.00 3.11 ± 1.75 20.74 ± 3.71 193.61 ± 7.65 2.65 ± 1.64
RvD1 (300 ng) + LPS 11.71 ± 3.62 99.42 ± 8.10*# 1.87 ± 2.15 17.41 ± 2.52 121.07 ± 8.46*# 2.19 ± 0.60 20.24 ± 2.78 155.77 ± 5.70*# 2.99 ± 0.46
RvD1 (600 ng) + LPS 10.70 ± 1.23 63.33 ± 2.09* 2.97 ± 2.27 10.39 ± 1.41 81.38 ± 8.00* 3.23 ± 1.38 14.50 ± 1.77 120.59 ± 9.59* 3.91 ± 1.59
GW9662 17.90 ± 4.40 0.21 ± 0.36 0.57 ± 0.34 26.48 ± 10.81 0.48 ± 0.66 1.71 ± 0.98 26.19 ± 12.49 0.30 ± 0.32 1.51 ± 1.22
GW9662 + RvD1 (600 ng) + LPS 13.02 ± 2.61 99.59 ± 7.15*# 2.72 ± 1.43 15.52 ± 0.71 113.52 ± 16.19*# 3.29 ± 0.58 14.15 ± 1.46 152.59 ± 2.91*# 3.60 ± 1.26

Data are mean ± SD, n = 3. BALF, bronchoalveolar lavage fluid. RvD1, resolvin D1. * p < 0.05 in comparison with the LPS group at each time point. # p < 0.05 in comparison with the RvD1 (600 ng) + LPS group at each time point.

Liao et al.

Liao et al. Respiratory Research 2012 13:110   doi:10.1186/1465-9921-13-110

Open Data