Effect of RvD1 on the LPS-activated DNA-binding ability of NF-κB in lung tissue. Lung tissue samples were collected at 6 h after LPS administration. (a) EMSAs were performed to detect the DNA-binding activity of NF-κB in nuclear extracts. (b) Histograms show the mean ± S.D. (n = 3) of the densitometric quantitation of DNA-binding activity by nuclear NF-κB relative to the control (saline). * p < 0.05 in comparison with the LPS group. # p < 0.05 in comparison with the LPS + RvD1 (600 ng) group. Representative results of three independent experiments with different mice are shown.
Liao et al. Respiratory Research 2012 13:110 doi:10.1186/1465-9921-13-110