Effects of RvD1 on histological changes in lung tissues of mice subjected to LPS-induced ALI. Lung tissue samples were collected at 24 h after LPS administration, and sections were stained with hematoxylin and eosin (H&E). Mice had been treated with the following: (a) saline, (b) 600 ng RvD1, (c) LPS only, (d) LPS + RvD1 (300 ng), (e) LPS + RvD1 (600 ng), (f) GW9662, (g) LPS + RvD1 (600 ng) + GW9662. (h) The degree of lung injury in tissue sections was assessed based on an ALI score. Values are expressed as mean ± SD (n = 3) .* p < 0.05 in comparison with the LPS group. # p < 0.05 in comparison with the LPS + RvD1 (600 ng) group. Scale bar = 100 μm.
Liao et al. Respiratory Research 2012 13:110 doi:10.1186/1465-9921-13-110