Table 6

Multiple linear regression examining the relationship of body composition, airway inflammation and systemic inflammation, with lung function in males.

ERV (mL)

Unadjusted Model

Final Model

R-squared = 0.681

p < 0.001


Variable

β-Coefficient (95% CI)

p-value

β-Coefficient (95% CI)

p-value


Lean Mass - Android (g)

0.29 (0.03, 0.55)

0.032

0.29 (0.03, 0.55)

0.032

Lean Mass - Gynoid (g)

0.3 (-0.1, 0.7)

0.082

%Sputum Eosinophils

19.67 (-6.24, 45.57)

0.125

Leptin (pg/mL)

0.025 (-0.002, 0.051)

0.063

Age (years)

-28.2 (-51.2, -5.2)

0.019

-40.3 (-58.0, -22.7)

< 0.001

Height (cm)

12.6 (-18.3, 43.5)

0.400

-9.5 (-40.8, 21.8)

0.529


FEV1/FVC

Unadjusted Model

Final Model

R-squared = 0.510

p <0.001


Variable

β-Coefficient (95% CI)

p-value

β-Coefficient (95% CI)

p-value


Lean Mass - Android (g)

-0.006 (-0.012, -0.002)

0.014

-0.007 (-0.012, -0.002)

0.014

%Sputum Neutrophils

0.1 (-0.1, 0.3)

0.149

%Sputum Eosinophils

-0.56 (-1.09, -0.03)

0.039

-0.6 (-1.0, -0.2)

0.009

CRP (pg/mL)

-2.3 (-4.0, -0.6)

0.010

Age (years)

-0.3 (-0.7, 0.2)

0.225

-0.2 (-0.6, 0.1)

0.141


ERV - expiratory reserve volume; FEV1 - forced expiratory volume in one second; FVC - forced vital capacity; CRP - C-reactive protein.

Scott et al. Respiratory Research 2012 13:10   doi:10.1186/1465-9921-13-10

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