Table 5

Relationship between body composition and systemic inflammation (leptin, CRP), airway inflammation and airway hyperresponsiveness in females.

Leptin (pg/mL)

CRP (pg/mL)

Neutrophils (%)

Neutrophils (× 104/mL)

Eosinophils (%)

Eosinophils (× 104/mL)

Dose Response Slope


Weight (kg)

0.391

0.199

0.218

0.263

-0.370

-0.291

-0.196

Waist Circumference (cm)

0.349

0.048

0.285

0.306

-0.125

-0.229

-0.045

Fat Mass (g)

Total

0.415

0.211

-0.040

-0.072

-0.506*

-0.385

-0.270

Android

0.260

0.240

0.029

0.068

-0.333

-0.315

-0.113

Gynoid

0.316

0.168

-0.115

0.032

-0.650**

-0.298

-0.480*

Thoracic

0.244

0.156

0.017

0.011

-0.413

-0.459

-0.209

Arms

0.317

0.036

0.026

-0.015

-0.031

-0.209

0.021

Legs

0.315

0.067

0.044

0.199

-0.438

-0.129

-0.362

Lean Mass (g)

Total

0.288

0.225

0.461

0.408

-0.048

-0.109

-0.060

Android

0.205

0.243

0.322

0.279

-0.042

-0.115

-0.122

Gynoid

0.232

0.247

0.544*

0.555*

-0.159

-0.038

-0.125

Thoracic

0.193

0.180

0.323

0.273

-0.149

-0.227

-0.127

Arms

0.277

0.111

0.227

0.171

-0.077

-0.231

0.270

Legs

0.309

0.045

0.709***

0.696**

0.070

0.119

0.087

%Fat

Total

0.216

0.110

-0.474*

-0.349

-0.448

-0.324

-0.296

Android

0.166

0.112

-0.298

-0.205

-0.353

-0.263

-0.050

Gynoid

0.188

0.103

-0.441

-0.337

-0.512*

-0.279

-0.451*

Thoracic

0.082

0.072

-0.306

-0.287

-0.334

-0.340

-0.133

Arms

0.317

-0.015

-0.076

-0.087

0.017

-0.094

-0.146

Legs

0.147

0.095

-0.345

-0.231

-0.445

-0.251

-0.420


CRP - C-reactive protein. Partial correlations are adjusted for height, age and pack years. * p≤0.05; ** p≤0.01; *** p≤0.001. † Provocation fall (%) ÷ provocation dose of 4.5% hypertonic saline (mL), after hypertonic saline challenge.

Scott et al. Respiratory Research 2012 13:10   doi:10.1186/1465-9921-13-10

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