Table 4

Relationship between body composition and systemic inflammation (leptin, CRP), airway inflammation and airway hyperresponsiveness in males.

Leptin (pg/mL)

CRP (pg/mL)

Neutrophils (%)

Neutrophils (× 104/mL)

Eosinophils (%)

Eosinophils (× 104/mL)

Dose Response Slope


Weight (kg)

0.533*

0.139

-0.200

-0.145

0.349

0.090

-0.198

Waist Circumference (cm)

0.608*

0.217

-0.177

-0.097

0.433

0.118

-0.220

Fat Mass (g)

Total

0.749**

0.406

-0.160

-0.039

0.382

0.107

-0.192

Android

0.726**

0.409

-0.225

-0.038

0.380

0.052

-0.272

Gynoid

0.499

0.232

-0.106

-0.230

0.294

-0.053

-0.213

Thoracic

0.675**

0.400

-0.232

-0.195

0.434

0.059

-0.305

Arms

0.597*

0.444

-0.017

-0.064

0.538*

0.228

-0.162

Legs

0.402

0.235

-0.096

-0.060

0.239

0.099

-0.077

Lean Mass (g)

Total

-0.120

-0.407

0.033

0.244

-0.062

0.225

-0.120

Android

0.333

0.005

-0.301

-0.029

0.344

0.379

0.242

Gynoid

0.084

-0.256

-0.242

-0.225

0.405

0.218

-0.223

Thoracic

0.051

-0.173

-0.258

-0.158

0.298

0.261

-0.206

Arms

-0.462

-0.136

-0.252

-0.186

-0.110

-0.020

0.027

Legs

-0.344

-0.604*

0.186

0.265

-0.395

0.005

-0.078

%Fat

Total

0.735**

0.502*

-0.220

-0.166

0.465

0.071

-0.137

Android

0.634*

0.407

-0.134

-0.090

0.267

-0.095

-0.395

Gynoid

0.507

0.346

-0.100

-0.255

0.311

-0.088

-0.109

Thoracic

0.681**

0.511*

-0.182

-0.182

0.416

-0.011

-0.248

Arms

0.658**

0.377

0.112

0.027

0.354

0.093

-0.246

Legs

0.498

0.439

-0.180

-0.192

0.418

0.103

-0.027


CRP - C-reactive protein. Partial correlations are adjusted for height, age and pack years. * p≤0.05; ** p≤0.01; *** p≤0.001. † Provocation fall (%) ÷ provocation dose of 4.5% hypertonic saline (mL), after hypertonic saline challenge.

Scott et al. Respiratory Research 2012 13:10   doi:10.1186/1465-9921-13-10

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