Table 1

Subject Characteristics.

Males

Females


N (%)

20 (45.5)

24 (54.5)

Age (years)

40.8 ± 11.4

38.8 ± 14.9

BMI (kg/m2)

32.2 ± 2.9

35.1 ± 3.6**

Waist Circumference (cm)

113.0 ± 10.1

107.8 ± 9.6

Total Body Fat (%)

35.2 ± 5.0

50.3 ± 3.8***

Android Fat (%)

46.2 (41.6, 51.5)

55.8 (52.7, 59.9)***

Gynoid Fat (%)

37.0 ± 4.6

55.6 ± 3.9***

Thoracic Fat (%)

35.4 ± 5.1

45.9 ± 4.9***

FEV1 %predicted

79.3 ± 19.5

83.3 ± 17.5

FVC %predicted

96.7 (84.0, 98.8)

96.4 (85.8, 107.9)

FEV1/FVC

66.5 (58.2, 78.9)

73.7 (67.1, 78.4)

TLC %predicted

98.1 ± 13.6

97.6 ± 12.0

FRC %predicted

101.5 ± 27.5

89.8 ± 19.0

ERV %predicted

112.2 (87.3, 130.4)

110.1 (93.3, 127.4)

Atopy (%)

100.0

78.3*

ICS Dose (μg/day) †

1000 (0, 1250)

1000 (0, 1000)

ICS Use (%)

70.0

70.8

Ever Smokers (%)

35.0

33.3

Pack Years of Ever Smokers

8 (1, 15)

3 (1, 7)

Age at Asthma Diagnosis (Years)

6 (2, 16)

8 (3, 18)

ACQ Score

1.2 ± 0.7

1.4 ± 0.5

GINA Classification (%)

Intermittent

25.0

12.5

Mild Persistent

20.0

29.2

Moderate Persistent

30.0

45.8

Severe Persistent

25.0

12.5

Systemic Inflammatory Markers

Leptin (μg/L)

6.2 (4.4, 10.9)

28.4 (19.7, 33.4)***

C-Reactive Protein (mg/L)

1.6 (0.9, 5.0)

4.8 (2.8, 8.3)**

Airway Inflammatory Markers

Total Cell Count (× 106/mL)

2.6 (2.1, 4.1)

2.0 (1.4, 5.6)

Neutrophils (%)

31.3 ± 19.8

35.5 ± 24.9

Neutrophils (× 104/mL)

752 (321, 1641)

1051 (277, 2709)

Eosinophils (%)

4.3 (2.2, 10.3)

1.3 (0.5, 3.3)*

Eosinophils (× 104/mL)

184 (68, 375)

100 (11, 133)*


Data presented as mean ± standard deviation, median (IQR) or % the percentage of subjects with the specified variable. BMI - body mass index; FEV1 - forced expiratory volume in one second; FVC - forced vital capacity; TLC - total lung capacity; FRC - functional residual capacity; ERV - expiratory reserve volume. * p≤0.05 versus males; ** p≤0.01 versus males; *** p≤0.001 versus males; † Beclomethasone equivalents.

Scott et al. Respiratory Research 2012 13:10   doi:10.1186/1465-9921-13-10

Open Data