Figure 6.

The relationships between the systolic pulmonary arterial pressure (Ppa) and the lung responsiveness expressed as the equivalent dose required to cause a 50% increase in the airway resistance (ED₅₀) in the different groups . CC: control group, CS: shunt, no treatments, VIP: shunt, treatment with VIP, ILO: shunt, treatment with iloprost, SIL: shunt, treatment with sildenafil, TEZ: shunt, treatment with tezosentan. Symbols: individual data points in each rat, thin lines: regressions for individual groups, thick line: linear regression for the pooled data.